One person has died after a truck collided with a car, in one of two crashes in 90 minutes on the Princes Freeway this morning.

The Prices Freeway is now completely closed out-bound and partially closed in-bound.

In the most serious crash, there was a collision before the Kororoit Creek Road out-bound exit ramp between a truck and car.

All Geelong-bound lanes are blocked at traffic is backed up to Millers Road.

Drivers are being told to consider using the M80 Ring Road, Boundary Road and Fitzgerald Road to return to the Princes Freeway.

The second crash happened between two cars Melbourne-bound and closed the middle lane.

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