A severely ill five-year-old boy in England has asked people to wear yellow on March 27 to support his second bone marrow transplant.

Seth Lane suffers from combined immunodeficiency, colloquially known as “bubble boy disease”, and has lived in a sterile environment for most of his life.

If his family comes into his hospital room, they first have to scrub and wear plastic gowns.

Seth’s first bone marrow transplant was unsuccessful, but as he prepares to undergo his second, his dad has filmed a touching clip asking for support online from strangers.

The video has racked up millions of views so far – something the little boy can barely believe.

“I told him about the views and he asked, ‘Is it more than 20?’ I said, ‘yes it is’ and he said, ‘wowee’,” mum Leanne told the Daily Mail.

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Seth’s parents want the photos to show him just how much support he has, and plan to hang them up around his hospital room.

His father, Nik, wrote on a blog, “We have a map of the world in his room and will pin all the countries where people have posted a picture from.”

To show your support for this brave little boy, post a pic of yourself in yellow with the hashtag #WearYellowForSeth.

The Lane family blogs at ourlittlehero.wordpress.com.